Collagen & Supplementation

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Hair and Cosmetics

Introduction

Good collagen is essential for good skin health. We have maximal collagen in our youth and over time it fades. Many of us want to age well and will focus on ensuring a good supply of our collagen. Many cosmetic procedures help to enhance and stimulate the growth of collagen such as laser, radiofrequency microneedling and the injection of filler simulates collagen in the body tissues. This article discusses how to obtain collagen from the diet and supplementation to help our skin as we age.

What is collagen?

Collagen is one of the body’s main structural proteins. It is found in skin, gut, eyes, cartilage, bones, tendons; 30% of the body’s protein store is collagen. Collagen is a tough structural protein; in fact, sausage skins are often made from it.

 

Where do we get our dietary collagen from?

The body will make collagen from amino acids and other cofactors. As we age, the rate of collagen production reduces. Also, we obtain collagens from our diet such as bone marrow broth, animal skins to name a few. Collagen in the diet comes from animal products only.

What happens as we lose collagen?

The collagen loss in ageing is well known; there is a general loss of connective tissue and firmness in the face leading to sagging. Also, the healing of tendons after injury can be slower as we age.

Are collagen supplementations useful?

Recently, there has been an increased interest in taking collagen supplements. In some instances, this is for cosmetic ageing repair and is similar to how people might take Hyaluronic Acid which is another connective tissue molecule.

A systematic review has been conducted by Choi et al (2019) showing generally positive data in the following way:

“Preliminary results are promising for the short and long-term use of oral collagen supplements for wound healing and skin ageing. Oral collagen supplements also increase skin elasticity, hydration, and dermal collagen density.”

Furthermore, studies have shown that oral collagen supplementation is associated with:

  • greater bone healing,
  • brittle nail repair,
  • Greater wound healing
  • Less skin ageing
  • Better skin elasticity, hydration and dermal collagen density

How effective are collagen supplements?

Research in this area is limited compared with many other treatments and you should not regard collagen as a panacea, but rather a supplement.

 

Collagen and Skin

The best studies are on skin and do show a benefit. The extent of this is hard to pinpoint. Some studies such as on skin only had follow up until 4 weeks but did show an improvement in skin indices by 10-30% and subjective patient satisfaction well over 50%. However, the improvements reduced by 45% after time had elapsed. This margin of improvement may matter more for older people rather than young.

Collagen supplementation should not be regarded as the only way to look after your skin; seek professional advice and do not forget your nutrition, zinc oxide chemical free sunlight and moisturisers.

 

Muscle gain and fat loss

Apart from skin, collagen has been used for muscle gain and fat loss; the change was only about a 5% reduction in fat mass and this was in an older population who generally have less muscle than the young. This study was done in the setting of resistance training so we cannot generalise the findings. Furthermore, collagen is an important source of many amino acids that are generally useful for building protein and may be responsible for the benefits seen.

 

Collagen for Joint Pains

Collagen supplementation has been studied for joint pains in athletes and found to have a benefit; however it should be remembered that this population uses their joints substantially more than most people. It should be noted that glucosamine has been studied more extensively and it actually increases Hyalouronic Acid, a connective tissue protein as well.

As always, speak to your general or orthopaedic doctor, nutritionist, physiotherapist before embarking on self treatment as there may be a better way to deal with your problem that you are missing out on.

How to take collagen?

In general, diet is always the first place to start. Have a good vegetable diet, minimise processed food and obtain bone broth, ligament and animal skin foods. Only take a supplement after discussion with your health care provider and optimising your diet and lifestyle first.

Those who may benefit from collagen will generally be those with more reason to take it such as skin laxity, joint pains, older and reduced muscle mass. It should also be noted that many studies were on western populations who have a different diet to other populations.

Oral collagen should be taken about 3g per day. It should be continued. Skin based Hyaluronic Acid is also an important adjunct to collagen preservation as well as a Zinc Oxide chemical free sun cream. However, remember the importance of natural sunlight which is best obtained before 9am and after 5pm so that you receive the vitamin D and mental benefits of this.

REFERENCES

Benito-Ruiz P, Camacho-Zambrano MM, Carrillo-Arcentales JN, et al. A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort. Int J Food Sci Nutr. 2009;60 Suppl 2:99-113. doi:10.1080/09637480802498820

Bolke L, Schlippe G, Gerß J, Voss W. A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo Controlled, Blind Study. Nutrients. 2019;11(10):2494. Published 2019 Oct 17. doi:10.3390/nu11102494

Choi FD, Sung CT, Juhasz ML, Mesinkovsk NA. Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. J Drugs Dermatol. 2019;18(1):9- 16.

Clark KL, Sebastianelli W, Flechsenhar KR, et al. 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Curr Med Res Opin. 2008;24(5):1485-1496. doi:10.1185/030079908×291967

Hexsel D, Zague V, Schunck M, Siega C, Camozzato FO, Oesser S. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. J Cosmet Dermatol. 2017;16(4):520-526. doi:10.1111/jocd.12393

König D, Oesser S, Scharla S, Zdzieblik D, Gollhofer A. Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A

Randomized Controlled Study. Nutrients. 2018;10(1):97. Published 2018 Jan 16. doi:10.3390/nu10010097

Zdzieblik D, Oesser S, Baumstark MW, Gollhofer A, König D. Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial.

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